bac arrays (BlueGnome Limited)
Structured Review

Bac Arrays, supplied by BlueGnome Limited, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bac+arrays/pmc09102663-108-3-10?v=BlueGnome+Limited
Average 90 stars, based on 1 article reviews
Images
1) Product Images from "Whole Genome Amplification in Preimplantation Genetic Testing in the Era of Massively Parallel Sequencing"
Article Title: Whole Genome Amplification in Preimplantation Genetic Testing in the Era of Massively Parallel Sequencing
Journal: International Journal of Molecular Sciences
doi: 10.3390/ijms23094819
Figure Legend Snippet: Clinical cycle of comprehensive preimplantation genetic testing. The process starts with family genetic testing in order to establish normal and disease-associated family haplotypes. Next, oocyte stimulation, retrieval, and fertilization are performed. Embryos surviving until day 5 undergo laser-assisted hatching and biopsy. Biopsy material consisting of a few trophectoderm cells is amplified using one of the WGA techniques. WGA material is further used to assess the embryonic genome, including haplotype, causative variant, aneuploidy, and CNV analyses. The disease-free embryo is subjected to embryo transfer to the uterine cavity. The whole cycle can be repeated within 24 h, with a day-6 embryo being transferred. If the genetic testing takes longer, then embryos are vitrified and thawed before being transferred. PGT—preimplantation genetic testing, WGA—whole-genome amplification, IVF—in vitro fertilization, MPS—massively parallel sequencing, CNV—copy number variation.
Techniques Used: Amplification, Variant Assay, Whole Genome Amplification, In Vitro, Sequencing
